Chocolate Drug Delivery System

Chocolate is extremely subtle a flexible food that’s combined to create utterly totally different style and texture sensations. Chocolate is also an associate degree anhydrous medium and is thus a proof against microbe growth and to chemical reaction of water-sensitive active agents. Chocolate is well-suited as a vehicle for delivering active agents in several aspects. For example, the organoleptic characteristics of chocolate are glorious for masking unpleasant flavors related to some active agents and giving a swish and creamy texture to compositions of active agents that are otherwise undesirably gritty. Chocolate product derived from cocoa (cacao), mixed with fat (i.e., cocoa butter) and finely granulated sugar to supply a solid confectionery. Medicated chocolate is ready by victimization chocolate base and therefore the drug is incorporated into ready chocolate base because the drug is incorporated at intervals the chocolate and therefore the drug is discharged from the chocolate, it’s known as Chocolate drug delivery system. Chocolate drug delivery system has benefits that embrace a possible bypass of first-pass effects and turning away of pre-systemic elimination at intervals the alimentary canal. Chocolate is additionally an associate degree anhydrous medium and is thus proof against microbe growth and to hydrolysis of water-sensitive active agents. Chocolate is well-suited as a vehicle for delivering active agents in several aspects.

One of the best challenges in medical specialty has been optimization of oral drug delivery. Crushing tablets might amend the speed or extent of drug absorption and thus bioavailability. Cutting tablets, another common follow, is also acceptable for a few medication, but this follow will introduce extensive variability between doses. Extemporary oral suspension or answer may be having issue with stability, handling, addition of seasoning agent or use of a special whole, might alter the stability of the ultimate product or the absorption characteristics of the drug. Commercially accessible oral liquid medications offer an additional reliable, ready-to-use preparation for infants and kids, but bioequivalence with solid oral indefinite quantity forms continues to be not assured.

PRANJUL SHRIVASTAVA

ASSISTANT PROFESSOR , FACULTY OF PHARMACY, KALINGA UNIVERSITY

Email : pranjul.shrivastava@kalingauniversity.ac.in